NOVEL THERAPY NEWS

New Treatments for Hepatitis C

                                                         … maybe

2008

July

Iran’s doing a generic form of Roche’s Pegasys.  It’s cheaper, so they can treat more of their citizens.  It reportedly works as well (which ain’t saying a whole bunch).  

Iran produces pegaferon for hepatitis C             

PRESS TV - Tehran,Iran

Iran has mass-produced pegaferon, a recombinant pegylated interferon (PEG-IFN) alpha-2a, effective in treating chronic hepatitis C. “We are now the second ...

May

Vertex v. Schering. Still, between the 2 of ‘em, between 11% & 17% of patients dropped out of the phase 2 studies due to side effects.  SVR rates ... a little over 50% for us geno 1’s.  (yawn) ....

Hep C Drugs Slug It Out

Motley Fool – USA

Last month, Vertex Pharmaceuticals (Nasdaq: VRTX) produced very strong study data on its lead antiviral hepatitis C drug telaprevir at the European ...

Schering’s protease inhibitor moves to phase III testing (a good study to get on, by the way).  Although we don’t really give a shit who gets there first.  Just get there!!! 

Vertex's Lead Cut Down

Motley Fool – USA

By Brian Lawler May 23, 2008 Comments (0) Schering-Plough (NYSE: SGP) is moving forward with its antiviral hepatitis C drug even faster than expected. ...

April

Here’s a possible new one that passed it’s baby step with the FDA.  Now they’re fixin’ to start a 2-week safety trial using this, Pegasys & copegus (Roche’s peg & riba combo).  Let’s keep our fingers crossed ....

InterMune: Trial of hepatitis C therapy showed top-line results

Forbes - NY,USA

NEW YORK (Thomson Financial) - InterMune Inc. Tuesday said a Phase 1b clinical trial of its experimental hepatitis C therapy, ITMN-191, showed treatment ...

This pharma presented their Hep C program at a hep C doc conference in N.Y. 

Idenix Pharmaceuticals to Present at the Canaccord Adams Hepatitis ...

Earthtimes - London,UK

CAMBRIDGE, Mass., April 4, 2008 -- Idenix Pharmaceuticals, Inc. announced today that Idenix management will present an overview of its Hepatitis C program ...

February

Scientists in the land down under work to bring us a vaccine for hep C.  ... cool.

New Hope for Hepatitis C Sufferers

Newswise (press release) – USA

Newswise — Adelaide scientists will lead a $2 million five-year project to develop new vaccines and explore better treatment options for hepatitis C ...

The first protease inhibitor out of the chute’s now looking at a problem of drug resistance – in other words, the virus beats the drug – adding this to their not-so-impressive numbers.

Vertex’s lead drug telaprevir for the treatment of Hepatitis C ...

Financial Times - London,England,UK

Reimbursement and pricing will also have to be taken into consideration, as many patients on Hepatitis C treatment have to take an additional EPO product to ...

January

While we could give a rip about Human Genome Sciences stock market rating, what happened here is that when they upped the dose in their clinical trial, people taking the drug started getting heart problems.  ... this we care about.

Human Genome Sciences shares fall on hepatitis C drug results

Daily Record (subscription) - Baltimore,MD,USA

... said it would modify trials of an experimental drug to treat hepatitis C after some patients receiving higher dosages experienced serious side effects. ...

Telapravir – formerly known as VX-950 – trial results: good news & bad news.  The bad news ... it doesn’t work; the good news: used with peg-interferon & ribavirin, it might cut the treatment time in half.  ... bummer.

Vertex Under the Gun

Motley Fool – USA

Vertex announced yesterday that it was advancing its lead hepatitis C drug, telaprevir, into phase 3 trials, yet the market promptly took its shares to lows ...

 2007

December 2007

One of the reasons treatment can be too hard to endure is cuz the peg interferon can cause an abrupt drop in our platelet counts.  Here’s some news stories on a drug that may be able to do something about that.

Eltrombopag Effective for Hepatitis C Patients With Low Blood ...

Newswise (press release) – USA

Newswise — For patients with hepatitis C, having a low blood platelet count is a frequent complication associated with advanced disease. ...

Eltrombopag effective for hepatitis C patients with low blood ...

HULIQ - Hickory,NC,USA     

For patients with hepatitis C, having a low blood platelet count is a frequent complication associated with advanced disease. This problem is compounded by ...

Drug helps boost blood-platelets in Hep C

Earthtimes - London,UK

28 A report in the New England Journal of Medicine says the drug eltrombopag appears to significantly boost platelet counts in hepatitis C patients. ...

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